Caryophyllene Oxide
Sesquiterpenoid (Bicyclic)
C15H24O
Abundance: Trace
When beta-Caryophyllene is exposed to oxygen, it undergoes an epoxidation reaction to form caryophyllene oxide. It does not bind to the CB2 receptor, meaning its biological activity is independent of the endocannabinoid system, but it boasts robust antifungal properties and is the primary compound targeted by law enforcement drug-sniffing dogs.
Pharmacology & Effects
- Antifungal (efficacy against onychomycosis)
- Inhibitor of central pain receptors
- Alters PI3K/AKT/mTOR pathways (increases proapoptotic proteins)
Aroma Profile
Earthy
Pepper
Woody
Dry
Spicy
Chemistry Specs
- Molar Mass
- 220.35 g/mol
- CAS Number
- 1139-30-6
Vaporization Data
Boiling Point
299 °C
570.2 °F